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PRP Skin Rejuvination

What is PRP/PRFM PLATELET RICH PLASMA/PLATELET RICH FIBRIN MATRIX

These are exciting autologous, non-surgical therapeutic options for patients who require stimulation of hair, scalp and skin.

The procedure involves drawing out one’s own blood and centrifuging it in a specially designed PRP kit. So, that the plasma with platelets is extracted from the blood sample. This plasma rich in platelets and growth factors is very useful in tissue regeneration and healing. It is then injected on the scalp or applied on the scalp after performing micro needling in the areas which suffers from hair loss.



Who should opt for PRP/PRFM?

People with thinning hair, androgenetic alopecia (male pattern baldness – hair loss at the top of the scalp and a receding hairline particularly along the temples) and women with male pattern alopecia can benefit from it.

Generally, the treatment requires about eight sittings, each two to three weeks apart for best results. Home care remedies are recommended along with the treatment course. Your doctor may also alternate between stem cell therapy and PRP as combination treatments have shown to provide good results.

To improve comfort of the patient, a numbing cream is applied on the area to be treated, prior to the procedure, which involves aseptic methods of phlebotomy (drawing out blood) and micro injections /micro needling on the area to be treated. The procedure is tolerated quite well without any pain, discomfort or ecchymosis.



What are the expected results?

Patients will soon see tufts of new baby hair on the treated area after the third or fourth sitting. The treatment not only promotes hair regrowth but also strengthens the hair follicles. Initial changes in hair density and quality are seen after 1-2 months of therapy. Changes will be assessed by comparing pre & post treatment photographs and non-invasive measurement of hair density at intervals of one month after initial treatment. It is quite a safe procedure without any side-effects.



Who can’t opt for PRP/PRFM?

Though PRP treatment yields great results for people suffering from hair loss, it’s not for everyone. Patients with history of heavy smoking, drug and alcohol use shows less prognosis. PRP/PRFM therapy is not advised in case of medical diagnosis such as platelet dysfunction syndromes, thrombocytopenia, hypofibrinogenaemia, hemodynamic instability, sepsis, acute and chronic Infections, chronic liver disease, anti-coagulation therapy, chronic skin diseases or cancer, metabolic and systemic disorders.



THE SCIENCE OF PRP/PRFM

PRP contains mesenchymal stem cells and autologous blood products which release essential and specific growth factors that assist in growth of the hair follicles by stimulating the stem cells located in the Dermal Papilla as well as other structures of the hair follicle. These special cells promotes healing, accelerates the rate and degree of tissue healing and regeneration, response of the body to injury, and formation of new cellular growth. The primary purpose of using PRP in hair restoration is to stimulate inactive or newly implanted hair follicles into an active growth phase. Inside the Platelets are many intracellular structures such as glycogen, lysosomes and alpha granules. These granules within the PRP contain clotting and growth factors that are eventually released during the healing and repair process. PRP specific cells that causes hair growth include: (CHART) Platelet-Derived Growth Factor (PDGF)—promotes blood vessel growth, cell replication, skin formation; Transforming Growth-Factor-Beta (TGF-b)—promotes growth of matrix between cells, bone metabolism; Vascular Endothelial Growth Factor (VEGF)—promotes blood vessel formation; Epidermal Growth Factor (EGF)—promotes cell growth and differentiation, blood vessel formation, collagen formation; Fibroblast Growth Factor-2 (FGF-2)—promotes growth of specialized cells and blood vessel formation; and, Insulin Like Growth Factor - (IGF)—a regulator of normal physiology in nearly every type of cell in the body.